Announcing! – the Sarcoma Central Science Spotlight winners

With this award, Sarcoma Central honors research that has accelerated the scientific understanding and treatment of sarcomas.

The top eight abstracts, drawn from the 2018 ASCO annual meeting and selected by Sarcoma Central’s Advisory Council, are shown below. With a nod to Joe Biden’s “collaboration… is where the solutions lie, and how we’ll end cancer as we know it,” members of Sarcoma Central, including featured authors, are invited to engage in discussions and data sharing around these works-in-progress. Through examination of the latest data, methods, results, and open questions, collective wisdom on these and related topics will move the needle toward better patient outcomes.

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The 2018 Science Spotlight Selections

Register or log in to Sarcoma Central to view the full abstracts at ASCO.org and to join the discussions via links below. Members can most easily follow ongoing conversations by joining the open group “SC Science Spotlight“. By joining this group, you’ll receive a weekly email digest of comments (by default) and/or immediate email notifications (by choice).

ASCO Abstract 11500

  • Phase III, randomized, double blind, placebo-controlled trial of sorafenib in desmoid tumors (Alliance A091105)

    Abstract | Discussion

  • Mrinal M. Gounder, Michelle R. Mahoney, Brian Andrew Van Tine, Vinod Ravi, Steven Attia, Hari Anant Deshpande, Abha A. Gupta, Mohammed M. Milhem, Robert Martin Conry, Sujana Movva, Michael J. Pishvaian, Jeffrey Crawford, Tarek Sabagh, Robert G. Maki, William D. Tap, Robert A Lefkowitz, Narasimhan P Agaram, John Joseph Wright, Amylou C. Dueck, and Gary K. Schwartz.
ASCO Abstract 11514

  • A phase 1 study of MDM2 inhibitor DS-3032b in patients with well/de-differentiated liposarcoma (WD/DD LPS), solid tumors (ST) and lymphomas (L)

    Abstract | Discussion

  • Todd Michael Bauer, Mrinal M. Gounder, Amy M. Weise, Gary K. Schwartz, Richard D. Carvajal, Prasanna Kumar, Oleg Zernovak, Alida Beck, Jana Doyle, Jeanne Mendell-Harary, Jarema Peter Kochan, Shuquan Chen, Patricia LoRusso, William D. Tap, Neeta Somaiah, David Michael Hyman, Funda Meric-Bernstam, and David S. Hong
ASCO Abstract 11515

  • IMMUNOSARC: A collaborative Spanish (GEIS) and Italian (ISG) Sarcoma Groups phase I/II trial of sunitinib plus nivolumab in selected bone and soft tissue sarcoma subtypes—Results of the phase I part

    Abstract | Discussion

  • Javier Martin Broto, Nadia Hindi, Andres Redondo, Javier Martinez-Trufero, Silvia Stacchiotti, Emanuela Palmerini, Enrique Alava, David Silva Moura, Herminia Perez Vega, Irene Otero, Patricio Ledesma, Emanuela Marchesi, Jose A. Lopez-Martin
ASCO Abstract 11516

  • A phase II study of talimogene laherparepvec (T-VEC) and pembrolizumab in patients with metastatic sarcoma

    Abstract | Discussion

  • Ciara Marie Kelly, Timothy Geoffrey Bowler, Rodrigo Ramella Munhoz, Ping Chi, Mark Andrew Dickson, Mrinal M. Gounder, Mary Louise Keohan, Reena Dholakia, Mercedes M. Condy, Samuel Singer, Aimee Marie Crago, Sam S. Yoon, Charlotte Eielson Ariyan, Sinchun Hwang, Joseph Patrick Erinjeri, Cristina R. Antonescu, Li-Xuan Qin, William D. Tap, and Sandra P. D’Angelo
ASCO Abstract 11517

  • Compared descriptive analysis of immunologic landscape in soft tissue sarcoma and GIST

    Abstract | Discussion

  • Armelle Dufresne, Tom Lesluyes, Mehdi Brahmi, Christine Menetrier-Caux, Christophe Caux, Jean-Yves Blay, and Frederic Chibon
ASCO Abstract 11549

  • Genomic alterations in the homologous recombination pathway in soft-tissue sarcomas

    Abstract | Discussion

  • Nathan David Seligson, Esko Antero Kautto, Edward N Passen, Colin W Stets, Amanda Toland, John L. Hays, and James Lin Chen
ASCO Abstract 11563

  • Discovery and characterization of novel, recurrent, targetable ALK fusions in leiomyosarcoma

    Abstract | Discussion

  • Lara Emily Davis, Kevin Nusser, Joanna Przybyl, Maria Debiec-Rychter, Janét Pittsenbarger, Nicolle Hofmann, Sushama Varma, and Monika Davare
ASCO Abstract 11581

  • Genomic amplification of CDK4 in dedifferentiated liposarcomas as a predictive biomarker for microtubule disrupting agents

    Abstract | Discussion

  • Bryce Demoret, Andrew Rogers, Nathan David Seligson, Esko Antero Kautto, John L. Hays, and James Lin Chen

Congratulations to the Star Scientists!

  • Narasimhan P. Agaram

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Enrique Alava

    Hospital Virgen del Rocío-IBis, Seville, Spain

  • Cristina R. Antonescu

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Charlotte Eielson Ariyan

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Steven Attia

    Mayo Clinic, Jacksonville, Florida

  • Todd Michael Bauer

    Sarah Cannon Research Institute/Tennessee Oncology, Nashville, Tennessee

  • Alida Beck

    Daiichi Sankyo Inc, Edison, New Jersey

  • Jean-Yves Blay

    Centre Léon-Bérard, Lyon, France

  • Timothy Geoffrey Bowler

    Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York

  • Mehdi Brahmi

    Centre Léon-Bérard, Lyon, France

  • Javier Martin Broto

    Virgen del Rocio University Hospital / Universidad de Sevilla, Spain

  • Richard D. Carvajal

    Daiichi Sankyo Co., Ltd., Collegeville, Pennsylvania

  • Christophe Caux

    Centre Léon-Bérard, Lyon, France

  • Shuquan Chen

    Memorial Sloan Kettering Cancer Center, New York, New York

  • James Lin Chen (2x)

    The Ohio State Comprehensive Cancer Center, Columbus, Ohio

  • Ping Chi

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Frederic Chibon

    INSERM-Université Toulouse and ICR-IUCT-ONCOPOLET, Toulouse France

  • Mercedes M. Condy

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Robert Martin Conry

    The Kirkland Clinic At Acton Road, Birmingham, Alabama

  • Aimee Marie Crago

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Jeffrey Crawford

    Duke University Medical Center, Durham, North Carolina

  • Sandra P. D’Angelo

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Monika Davare

    Oregon Health & Science University, Portland, Oregon

  • Lara Emily Davis

    Oregon Health & Science University, Portland, Oregon

  • Maria Debiec-Rychter

    KU Leuven, Leuven, Belgium

  • Bryce Demoret

    The Ohio State University Wexner Medical Center, Columbus, Ohio

  • Hari Anant Deshpande

    Yale Cancer Center, New Haven, Connecticut

  • Reena Dholakia

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Mark Andrew Dickson

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Jana Doyle

    Daiichi Sankyo Inc, Edison, New Jersey

  • Amylou C. Dueck

    Mayo Clinic, Scottsdale, Arizona

  • Armelle Dufresne

    Centre Léon-Bérard, Lyon, France

  • Joseph Patrick Erinjeri

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Mrinal M. Gounder (3x)

    Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York

  • Abha A. Gupta

    Princess Margaret Cancer Centre, Toronto, Canada

  • John L. Hays (2x)

    The Ohio State University Wexner Medical Center, Columbus, Ohio

  • Nadia Hindi

    Virgen del Rocio University Hospital, Institute of Biomedicine Research / Universidad de Sevilla, Spain

  • Nicolle Hofmann

    Oregon Health & Science University, Portland, Oregon

  • David S. Hong

    MD Anderson Cancer Center, Houston, Texas

  • Sinchun Hwang

    Memorial Sloan Kettering Cancer Center, New York, New York

  • David Michael Hyman

    MD Anderson Cancer Center, Houston, Texas

  • Esko Antero Kautto (2x)

    The Ohio State Comprehensive Cancer Center, Columbus, Ohio

  • Ciara Marie Kelly

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Mary Louise Keohan

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Jarema Peter Kochan

    Yale University School of Medicine–Yale Cancer Center, New Haven, Connecticut

  • Prasanna Kumar

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Patricio Ledesma

    Hospital 12 de Octubre Avda de Córdoba, Madrid, Spain

  • Robert A Lefkowitz

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Tom Lesluyes

    Institut Bergonié, Bordeaux, France

  • Jose A. Lopez-Martin

    Medical Oncology Department, Hospital 12 de Octubre, Madrid, Spain

  • Patricia LoRusso

    MD Anderson Cancer Center, Houston, Texas

  • Michelle R. Mahoney

    Mayo Clinic, Rochester, Minnesota

  • Robert G. Maki

    Monter Cancer Center, Northwell Health / Cold Spring Harbor Laboratory, Lake Success, New York

  • Emanuela Marchesi

    Sofpromed Investigación Clínica, Palma De Mallorca, Spain

  • Javier Martinez-Trufero

    Hospital Universitario Miguel Servet, Zaragoza, Spain

  • Jeanne Mendell-Harary

    Daiichi Sankyo Inc, Basking Ridge, New Jersey

  • Christine Menetrier-Caux

    Claude Bernard University, Lyon, France

  • Funda Meric-Bernstam

    MD Anderson Cancer Center, Houston, Texas

  • Mohammed M. Milhem

    Holden Comprehensive Cancer Center, Iowa City, Iowa

  • David Silva Moura

    Virgen del Rocio University Hospital / Universidad de Sevilla, Seville, Spain

  • Sujana Movva

    Fox Chase Cancer Center, Philadelphia, Pennsylvania

  • Rodrigo Ramella Munhoz

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Kevin Nusser

    Oregon Health & Science University, Portland, Oregon

  • Irene Otero

    Virgen delHospital Universitario Virgen del Rocio / Universidad de Sevilla, Seville, Spain

  • Emanuela Palmerini

    Istituto Ortopedico Rizzoli, Bologna, Italy

  • Edward N Passen

    The Ohio State Comprehensive Cancer Center, Columbus, Ohio

  • Michael J. Pishvaian

    Georgetown University Medical Center, Washington DC

  • Janét Pittsenbarger

    Oregon Health & Science University, Knight Cancer Institute, Portland, Oregon

  • Joanna Przybyl

    Stanford University School of Medicine, Stanford, California

  • Li-Xuan Qin

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Vinod Ravi

    MD Anderson Cancer Center, Houston, Texas

  • Andres Redondo

    Hospital Universitario La Paz, Madrid, Spain

  • Andrew Rogers

    The Ohio State Comprehensive Cancer Center, Columbus, Ohio

  • Tarek Sabagh

    Hematology/Oncology, Dayton Physicians Network, Inc., Dayton, Ohio

  • Gary K. Schwartz (2x)

    Columbia University Medical Center, New York, New York

  • Nathan David Seligson (2x)

    The Ohio State University College of Pharmacy / Baptist Memorial Healthcare, Columbus, Ohio

  • Samuel Singer

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Neeta Somaiah

    MD Anderson Cancer Center, Houston, Texas

  • Silvia Stacchiotti

    Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

  • Colin W Stets

    The Ohio State University College of Medicine, Columbus, Ohio

  • William D. Tap (3x)

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Amanda Toland

    The Ohio State University Wexner Medical Center, Columbus, Ohio

  • Brian Andrew Van Tine

    Washington University in St. Louis, Missouri

  • Sushama Varma

    Stanford University School of Medicine, Stanford, California

  • Herminia Perez Vega

    Virgen del Rocio University Hospital / Universidad de Sevilla, Seville, Spain

  • Amy M. Weise

    Karmanos Cancer Institute, Detroit, Michigan

  • John Joseph Wright

    National Cancer Institute, National Institutes of Health, Bethesda, Maryland

  • Sam S. Yoon

    Memorial Sloan Kettering Cancer Center, New York, New York

  • Oleg Zernovak

    Daiichi Sankyo, Inc, Edison, New Jersey

 

This initiative is generously supported by the Andrew W. Mellon Foundation, Bayer, EMD Serono, Eli Lilly, the Gordon & Betty Moore Foundation, Janssen Pharmaceuticals, the Mellon Foundation, the National Institutes of Health, and the Peaked Hill Fund.